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Frailty is a geriatric syndrome, characterized by a loss in functional reserve with an increase in morbidity and mortality. There are no reports that link the genetic polymorphisms between interleukin 10 IL10 and frailty; for this reason, our objective was used to analyze the role of the polymorphisms of IL10 rs, rs in the susceptibility to frailty in a Mexican population. Our study included participants divided into nonfrail, prefrail, and frail. This study evaluated the relationship between IL10 and the three subtypes of this geriatric syndrome frail, prefrail, and nonfrail.

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